Development of enzymes useful for human society, such as plastic-degrading enzymes


plastic degrading enzyme

Materials used for plastic, especially PET (polyethylene terephthalate), which is used for PET bottles, are difficult to decompose in nature. However, in recent years, microorganisms and microbial enzymes that can decompose PET have been found. This means that PET decomposition by enzymes is possible and may contribute to solving the problem of marine plastic waste. For the efficient decomposition of PET, even when using enzymes, it is preferable to process it at high temperatures. Therefore, we are developing a thermostable PET-degrading enzyme that can be used for enzyme decomposition at high temperatures, using ancestral reconstruction, consensus design, molecular evolution, and rational design methods.
 We are also working on developing enzymes that can be useful in food and beverage manufacturing, pharmaceutical synthesis, and solving environmental issues.

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